In the attached example, can the change address be identified with 100% certainty?
No.
Is there a potential scenerio where it could be the first one, and a potential where it could be the second (without knowing more details about who sent it, what wallet they used etc).
Yes.
There are a lot of heuristics that can be used to determine which output is the change output. However there are also a lot of ways that wallets can combat this. Without having the wallet that created the transaction, it is impossible to know with 100% certainty which is the change address.
(ie the odds are overwhelming that it is the 2nd smaller amount for example)
In your example, you use what is referred to as the unnecessary input heuristic. This heuristic relies on the assumption that a wallet is not going to include extra inputs to make a payment that could be covered by fewer inputs. Because the second output in your example is smaller than any one of the inputs, if it were the payment, then the transaction has an unnecessary input so it is likely that output is not the payment.
But wallet developers know that this is a heuristic used to determine change. So some wallets actually do exactly what this heuristic assumes to be false. Such wallets will sometimes make a change output that is greater than the payment amount. This breaks the heuristic.
There are a number of other techniques that can be used to determine which output is change, but each heuristic relies on an assumption that wallet developers can also break.