When I am asked to make donations, I assure the requester that I will donate if they accept BTC. Initially, that gets a blank look, but I wonder how it might change if more of us took that approach. Specifically, has anyone had success with making donations, political, religious or otherwise, using BTC?
Yes, there is a number of organizations and projects that accept Bitcoin donations.
The above linked list includes political parties (e.g. Libertarian Party in the US), at least one church (St. John's in Goshen, NY), a score of open-source projects, as well as a number of charities and other causes.