This transaction is contained in two MainChain-Blocks:
https://blockchain.info/tx/e3bf3d07d4b0375638d5f1db5255fe07ba2c4cb067cd81b84ee974b6585fb468
On Blockexplorer there is a note of this anomaly:
https://blockexplorer.com/block/00000000000743f190a18c5577a3c2d2a1f610ae9601ac046a38084ccb7cd721
As I understand, those 50 BTC are lost because only one of the rewards can be redeemed.
If so there will never be 21 million Bitcoin available, because those, or more of this sort, are missing?