Would prefer memory intensive rather than processor intensive proofs of work. ASICs make too exclusive and small the number for who possible mining is. 51% attack real worry for bitcoin.
51% attack can destroy bitcoin value completely. May not be profitable in bitcoin but possible do for reasons other. Imagine Chinese gov't considering people bypassing currency controls, or worse funding "terrorists" who want free speech. If is considered "Existential Threat", expect no hesitation on part of gov't to spend enough to destroy network, even when not profitable the destruction.
Also consider financial businesses eating whose lunch is bitcoin. What problem has toll troll making $Trillions on transaction fees spending a few $Billion to protect business from impending destruction?
Proof of work amenable to custom ASICs is worrying like finding half a worm in remaining apple.