While reading through the bitcoin wiki I found this following segment describing a bitcoin RPC safe-mode
Until version 0.3.20, Bitcoin went into safe mode when a valid alert was received. In safe mode, all RPC commands that send BTC or get info about received BTC return an error. Current Bitcoin versions no longer go into safe mode in response to alerts, though Bitcoin will still go into safe mode when it detects on its own that something is seriously wrong with the network.
Even though Bitcoin no longer automatically disables RPC when an alert is live, it is wise for Bitcoin sites to shut down when an alert has been issued. To detect an active alert, poll the "errors" field of getinfo.
To test safe mode, run Bitcoin with the -testsafemode switch. To override a real safe mode event, run Bitcoin with the -disablesafemode switch.
It says "Bitcoin will still go into safe mode when it detects on its own that something is seriously wrong with the network." I am interested in learning which events would make bitcoin go in to safe mode on it's own.